OJ Simpson, the controversial former NFL star who also pursued an acting career, has died of cancer at the age of 76. Simpson was a running back for the Buffalo Bills and San Francisco 49ers, before being acquitted of murder in a trial in the mid-1990s and was later jailed for his role in an armed robbery.

His children announced the news of his death on X, saying: “On April 10, our father, Orenthal James Simpson, succumbed to his battle with cancer. He was surrounded by his children and grandchildren. During this time of transition, his family asks that you please respect their wishes for privacy and grace. -The Simpson Family.”

It was reported last year that Simpson had been diagnosed with prostate cancer.

Dr Jiri Kubes, radiation oncologist and medical director of the Proton Therapy Center in Prague, Czech Republic, said: “Prostate cancer in the early stages can be hard to diagnose because it often comes without symptoms.

“However, men should keep a close eye on any changes in urinary habits including needing to go to the toilet more often and difficulty emptying their bladder. These changes don’t necessarily mean someone has prostate cancer, but there are checks that can be carried out to rule out such a diagnosis.

“Further symptoms we often see in our patients are difficulty in starting to urinate or a weak flow, as well as blood or semen in the urine. It is vital men know what to look out for and speak to their doctor if they have any concerns at all.

“GPs can ask for a blood test which measures levels of prostate-specific antigen, referred to as a PSA test. Physical exams and biopsies can also help to confirm a diagnosis.

“We don’t know the causes of prostate cancer but we do know some men are more at risk than others. They include men over the age of 50, members of the black community and anyone with a family history of the disease.

“It’s really important for anyone who falls into these groups to keep a close eye on their health and speak with their GP if they are concerned. Diagnosis of prostate cancer can be a devastating blow for men, but catching it as early as possible is key and the treatment options are improving.”